Setting up a NodeJS application on a FreeBSD 10 system was impossible when using ZFS as a file system. This was a real pain for me because when I tried out various stuff in jails rendered the whole system unusable, forcing me to reboot and this is not something one would do in a production environment.

Here’s the bug report: https://bugs.freebsd.org/bugzilla/show_bug.cgi?id=209158

Although I couldn’t read it from the bug it seems to be resolved now with FreeBSD 11-RELEASE because I’m running two Node applications on FreeBSD without any of the issues that were reproducible each time.